The overshoot phenomenon in step‐and‐shoot IMRT delivery
نویسندگان
چکیده
The control loop in the Varian DMLC system (V4.8) requires approximately 65 msec to monitor and halt the irradiation of a segment, causing an "overshoot" effect: the segment ends on a fractional monitor unit larger than that planned. As a result, the actual MU delivered may differ from that planned. In general, for step-and-shoot treatments, the first segment receives more, the last receives less, and intermediate segments vary. The overshoot for each segment (DeltaMU) is small, approximately 0.6 MU at 600 MU/min. Our IMRT planning system (Corvus) produces plans often having more than 20% of the segments with less than 1 MU/segment. Such segments may be skipped if the DeltaMU exceeds the segments' planned MU. Furthermore, QA filming often requires reducing the total MU by a factor of 4-6, increasing the potential for dosimetric error. This study measured DeltaMU over a range of MU/min and MU/segment. At >5 MU/segment, the DeltaMU was stable, corresponding to a delay of 62 msec. DeltaMU became larger and more variable at <1 MU/segment. The behavior was modeled in a computer program that predicted the change in delivered MU/segment and total change in delivered MU to each beamlet. Beams were analyzed for patients receiving 5 field prostate or 9 field head and neck treatments. At 400 MU/min, 28% and 16%, respectively, of the planned segments were skipped. For QA filming, up to 75% of the segments were skipped. The cumulative error averaged <0.1 MU/beamlet, but individual beamlets had errors exceeding 200%. The effect is most significant for low dose regions. Recommendations are given for deciding when to treat or do QA studies with lower MU/min. In general, treatments are not significantly affected, but QA films taken at reduced MU may be improved if irradiated at lowered MU/min.
منابع مشابه
The step‐and‐shoot IMRT overshooting phenomenon: a novel method to mitigate patient overdosage
The goal of this work is to evaluate the dosimetric impact of an overshooting phenomenon in step-and-shoot IMRT delivery, and to demonstrate a novel method to mitigate the issue. Five pelvis IMRT patients treated on Varian 2100C EX linacs with larger than +4.5% phantom ion chamber point-dose difference relative to planned dose were investigated. For each patient plan, 5 fractions were delivered...
متن کاملClinical implications of the overshoot effect for treatment plan delivery and patient‐specific quality assurance for step‐and‐shoot IMRT
In this work, overshoot and undershoot effects associated with step-and-shoot IMRT (SSIMRT) delivery on a Varian Clinac 21iX are investigated, and their impact on patient-specific QA point dose measurements and treatment plan delivery are evaluated. Pinnacle3 SSIMRT plans consisting of 5, 10, and 15 identical 5 × 5 cm2 MLC defined segments and MU/segment values of 5 MU, 10 MU, and 20 MU were ut...
متن کاملAssessment and Comparison of Homogeneity and Conformity Indexes in Step-and-Shoot, Compensator-Based Intensity Modulated Radiation Therapy (IMRT) and Three-Dimensional Conformal Radiation Therapy (3D CRT) in Prostate Cancer
Introduction: Intensity modulated radiation therapy (IMRT) and three-dimensional conformal radiation therapy (3D CRT) are two treatment modalities in prostate cancer, which provide acceptable dose distribution in tumor region with sparing the surrounding normal tissues. IMRT is based on inverse planning optimization; in which, intensity of beams is modified by using multileaf c...
متن کاملStep-and-Shoot versus Compensator-based IMRT: Calculation and Comparison of Integral Dose in Non-tumoral and Target Organs in Prostate Cancer
Introduction Intensity-Modulated Radiotherapy (IMRT) is becoming an increasingly routine treatment method. IMRT can be delivered by use of conventional Multileaf Collimators (MLCs) and/or physical compensators. One of the most important factors in selecting an appropriate IMRT technique is integral dose. Integral dose is equal to the mean energy deposited in the total irradiated volume of the p...
متن کاملRotational IMRT techniques compared to fixed gantry IMRT and Tomotherapy: multi-institutional planning study for head-and-neck cases
BACKGROUND Recent developments enable to deliver rotational IMRT with standard C-arm gantry based linear accelerators. This upcoming treatment technique was benchmarked in a multi-center treatment planning study against static gantry IMRT and rotational IMRT based on a ring gantry for a complex parotid gland sparing head-and-neck technique. METHODS Treatment plans were created for 10 patients...
متن کامل